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  • Immagine del redattoreElisabetta Mereu

2 Postdocs in single-cell genomics wanted: Revolutionizing B-cell leukemias and multiple myeloma treatments through ML and scGenomics

Are you interested in immunology, single-cell genomics and machine learning? Are looking for an exciting opportunity to work in biomedical research? The Mereu's lab at the Josep Carreras Leukemia Research Institute is seeking ambitious and motivated postdocs to join her team working on a comprehensive research program aimed at revolutionizing the monitoring, treatment and outcome of Leukemias and Multiple Myeloma patients.

B-cell neoplasms, such as B-cell Acute Lymphoblastic Leukemia (B-ALL) and Multiple Myeloma (MM), are hematologic malignancies that have high rate of relapse and limited treatment options. Therefore, it is crucial to identify patients at higher risk for relapse and tailor their treatments accordingly. In these projects a detailed, longitudinal single-cell map of T cell states in patients who have responded to therapy and those with insufficient partial response are generated. By analyzing the clonal dynamics of these T cells over time, you will gain a deeper understanding of how the immune system responds to therapies and how this response relates to disease progression. Additionally, you will be involved in the development of Machine Learning (ML) tools that will use these data to predict the evolution of the distinct disease patterns over time.

These postdoc positions are open to international applicants for co-fund Marie Curie programs in Spain (opening soon!!). The candidate should have a PhD degree at the date of the call deadline, and comply with the mobility rule (applicants must not have resided or carried out their main activity in Spain for more than 12 months in the 36 months immediately before the call deadline). Any nationality/age is eligible.

The successful candidate should have a background and experience in machine learning and/or single-cell genomics and immunology, with strong programming skills and good communication and writing skills.

As a member of our team, you will work closely with our multidisciplinary group of researchers, including 1 postdoc, 4 PhD students and 1 research assistant. The Mereu's team has diverse backgrounds in human biology, genetics, mathematics and systems engineering. They collaborate closely with clinicians from the Hospital Clinic of Barcelona, the Instituto Catalan de Oncologia (ICO), the Hospital Clinic of Barcelona and the Biomedical Can Ruti campus to obtain samples from patients and develop new strategies for diagnosis, treatment, and clinical management of patients.

This is a unique opportunity to contribute to a cutting-edge research program that will lead to a more personalized approach to treat and improve outcomes for patients. Our research has the potential to make a significant impact on the lives of patients and represents a promising path towards more effective precision medicine. Contact with us at to join the team and contribute to this exciting research endeavor. Please send your informal Expression of interest ASAP.

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