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  • Immagine del redattoreElisabetta Mereu

Computational Postdoc Wanted: Revolutionizing Multiple Myeloma Treatment through ML and scGenomics

Are you a computational postdoc with expertise in machine learning and single-cell genomics looking for an exciting opportunity to work in biomedical research? The Mereu's lab at the Josep Carreras Leukemia Research Institute is seeking an ambitious and motivated computational postdoc to join our team working on a comprehensive research program aimed at revolutionizing Multiple Myeloma (MM) treatment and improving patient outcomes.

MM is a hematologic malignancy with a high rate of relapse and limited treatment options, and it is crucial to identify patients at high risk for relapse and tailor their treatment accordingly. In this project, we will generate a detailed, longitudinal single-cell map of T cell states in MM patients who have responded to first-line therapy and those with insufficient partial response. By analyzing the clonal dynamics of these T cells over time, we will gain a deeper understanding of how the immune system responds to MM and how this response relates to disease progression. Additionally, we are interested in the development of a Machine Learning (ML) tool that will use these data to predict the evolution of the disease over time.

This postdoc position is open to international applicants for the Marie Curie 2023 program. The candidate should have a PhD degree at the date of the call deadline, and comply with the mobility rule (applicants must not have resided or carried out their main activity in Spain for more than 12 months in the 36 months immediately before the call deadline). Any nationality/age is eligible.

The successful candidate should have a background and experience in machine learning and single-cell genomics, with strong programming skills and good communication and writing skills.

As a member of our team, you will work closely with our multidisciplinary group of researchers, including 4 PhD students, 1 research assistant, and 1 bachelor student. Our team has diverse backgrounds in human biology, genetics, mathematics and systems engineering. We collaborate closely with clinicians from the Hospital Clinic of Barcelona, the Instituto Catalan de Oncologia (ICO), and the Biomedical Can Ruti campus to obtain samples from patients and develop new strategies for diagnosis, treatment, and clinical management of patients.

This is a unique opportunity to contribute to a cutting-edge research program that will lead to a more personalized approach to MM treatment and improve outcomes for patients. Our research has the potential to make a significant impact on the lives of patients and represents a promising path towards more effective precision medicine. Contact with us at to join our team and contribute to this exciting research endeavor. Expression of interest by April, 28, 2023.

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