Cellular Systems Genomics Lab

We strive to offer optimized analytical frameworks and creative uses of single-cell genomics to fight chronic diseases.

Research

In the interface between genomics, digital pathology and artificial intelligence our

goal is to define the cellular organization of complex tissues in health and diseases, particularly in the

context of autoimmunity and other chronic diseases.

By combining cutting edge technologies with machine learning, we enable the spatially resolved

molecular profiling of tissues at the highest resolution, facilitating the identification of key

regulatory mechanisms driving heterogeneity in cellular identity

and function.

News & Events

Marie Sklodowska-Curie Postdoctoral Fellowship (MSCA-Fellow)

The Cellular Systems Genomics Group at the Josep Carreras Research Institute is looking for a postdoc candidate of a MSCA fellowship! If...

We welcome Ane Martinez to the lab!

Ane Martinez is a new PhD student of the Cellular and Systems Genomics Group, lead by Dr. Elisabetta Mereu, and the Endothelial...

Join us as a PhD student within the INPhINIT program (deadline: 27 January 2022).

The INPhINIT-Incoming doctoral program consists of 35 fellowships for early-stage researchers of any nationality to pursue their PhD...

New research reveals differences between glioblastoma core and invasive cells

Glioblastoma cell fate is differentially regulated by the microenvironments of the tumour bulk and infiltrative margin. Glioblastoma...

Latest Publications

A Single-Cell Tumor Immune Atlas for Precision Oncology

The tumor immune microenvironment is a main contributor to cancer progression and a promising therapeutic target for oncology. However, immune microenvironments vary profoundly between patients and biomarkers for prognosis and treatment response lack precision. A comprehensive compendium of tumor immune cells is required to pinpoint predictive cellular states and their spatial localization.